Varicose veins (varicosis) is one of the most frequent vascular pathologies in the world. Etiological factors behind it are the following:
- inherited predisposition – the presence of varicosis in both parents raises the risk of the disease inheritance to 60%;
- gender — varicosis is observed in women 1.5–2 times more often than in men;
- excessive body weight – its increase by 20% leads to a 5 times higher risk of varicose vein disease in lower extremities (Sabelnikov V.V., Shulepova E.K., 2001);
- longtime static loads and poor motion activity.
In order to prevent the development of varicosis or to stop its progression a set of measures is needed: revise the diet, give up smoking, wear comfortable shoes, walk often.
For treatment and prevention of varicosis complications, the specialists recommend oral venotonic medicines.
The horse chestnut extract has a venotonic, vasoprotective, capillary-protective, anti-edema, anti-coagulation and antiphlogistic effect (Korsun V.F. et al., 2009). It allows the drug to influence the problem (varicosis and venous insufficiency) simultaneously in three directions by elevating the vein tonus, improving the venous blood flow and reducing the edema (Kiriyenko A.I. et al., 2010).
- Clinical trials suggest that medicinal products of horse chestnut extract promote a significant reduction of symptoms of the chronic venous insufficiency (Piechal A. et al., 2005).
- Good tolerance to the horse chestnut extract ensures a good compliance of its medicinal products, that is the readiness of patients to fully comply with doctor's and pharmacist's recommendations (Antignani P.L., Caliumi Ch., 2007).
- The horse chestnut extract is the most frequently prescribed venotonic drug in Europe.
