Neuropathy

We aimed to summarise recent advances in the therapy of diabetic neuropathy. Although all therapeutic choices in the treatment of diabetes mellitus itself are based on clear pathophysiological basis, this approach is less present in the treatment of the “forgotten complication”, diabetic neuropathy. As part of pathogenetic oriented treatment, the role of glycemic control and cardiovascular risk factors are reviewed.

Alpha-lipoic acid is a potent antioxidant that can be used for treatment and prevention of a wide range of diseases. The capacity of alpha-lipoic acid to influence the inflammation, apoptosis, blood flow, endothelial dysfunction, activation of neurotransmitters, and metabolic processes allows to consider it as a potential medicinal agent for various medical applications.

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