Alpha-lipoic acid is a potent antioxidant that can be used for treatment and prevention of a wide range of diseases. The capacity of alpha-lipoic acid to influence the inflammation, apoptosis, blood flow, endothelial dysfunction, activation of neurotransmitters, and metabolic processes allows to consider it as a potential medicinal agent for various medical applications.
Alpha-lipoic acid is a potent antioxidant with a unique capability to dissolve both in fats and water, and to function both on the cell membrane and in the cytoplasm. Alpha-lipoic acid has been proven to posses an independent antioxidant potential and to provide an additional potent support to other antioxidant components functioning in the body.
At present, there is a sufficient evidence base for the use of alpha-lipoic acid confirming its high clinical efficacy and safety in diabetic neuropathy management.
Administration of alpha-lipoic acid in patients with moderate manifestations of diabetic neuropathy can eliminate numbness and paresthesia, enhance neuromyographic parameters by improving the speed and potential of sensory nerve conductivity.
High efficacy, good tolerance, no or minor side effects determine the choice of alpha-lipoic acid for treatment of patients with diabetes mellitus, chronic liver diseases, intoxications and lesions of the peripheral nervous system.
