Hyperthyroidism Manifesting as Clinical Jaundice: A Report of a Rare Case

Deepak Jain¹, Aggarwal H.K.¹, Suhas Singla¹, Sunil Pawar¹, Promil Jain², Anshul Mittal^1
1Pt BD Sharma PGIMS, Department of Medicine, Rohtak, India
²Pt BD Sharma PGIMS, Department of Pathology, Rohtak, India

Summary. Thyroxine and triiodothyronine regulate the basal metabolic rate of all cells, including hepatocytes, and thereby, modulate hepatic function. Thus, thyroid dysfunction may perturb liver function. Though a wide spectrum of hepatic abnormalities has been attributed to hyperthyroidism with or without complications, such abnormalities are rare to be found and require high index of suspicion. In this case report, we present a female patient who was admitted with the complaints of generalized weakness, jaundice and shortness of breath. She initially had clinical presentation similar to that of congestive cirrhosis, but eventually proved to be a case of hyperthyroidism leading to hepatic dysfunction.

Key words: hyperthyroidism, jaundice, hepatic dysfunction.

Published in the «International Endocrinology Journal» №7(71)'2015